CONTINUING BESIFOVIR DIPIVOXIL MALEATE VERSUS SWITCHING FROM TENOFOVIR DISOPROXIL FUMARATE FOR TREATMENT OF CHRONIC HEPATITIS B: RESULTS OF 192-WEEK PHASE 3 TRIAL

Background/Aims Besifovir dipivoxil maleate (BSV), an acyclic nucleotide phosphonate, shows potent antiviral activity against hepatitis B virus.Our previous 48-week trial revealed that BSV has comparable antiviral efficacy to tenofovir disoproxil fumarate (TDF) and better safety profiles in terms of improved renal and bone safety.This extension stu

A new approach to security issues associated with the use of teleinformatics systems in the decision-making process has been presented.There is a discussion of the relationship between the security of informatics systems and the VIT D3 security of the decision-making process in which they are used, in particular regarding the threats resulting from

Abstract Perennial shrub willow are increasingly being promoted in short-rotation coppice systems as biomass feedstocks, for phytoremediation applications, and for the diverse ecosystem services that can accrue.This renewed interest has led to widespread willow cultivation, particularly of non-native varieties.However, Canadian willow species have

In the article the authors pay attention to the detention Ball - Bag - Personal on remand, which is the most serious procedural interference in the system of criminal law means to the personal liberty of an individual, accused of a crime.This institute is characterised in terms of national and international aspects of protection of the individual w